Package: BisqueRNA 1.0.5

Brandon Jew

BisqueRNA: Decomposition of Bulk Expression with Single-Cell Sequencing

Provides tools to accurately estimate cell type abundances from heterogeneous bulk expression. A reference-based method utilizes single-cell information to generate a signature matrix and transformation of bulk expression for accurate regression based estimates. A marker-based method utilizes known cell-specific marker genes to measure relative abundances across samples. For more details, see Jew and Alvarez et al (2019) <doi:10.1101/669911>.

Authors:Brandon Jew [aut, cre], Marcus Alvarez [aut]

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BisqueRNA/json (API)

Peer review:

Bug tracker:https://github.com/cozygene/bisque/issues

On CRAN:

6 exports 68 stars 3.56 score 6 dependencies 110 scripts 855 downloads

Last updated 3 years agofrom:8640250dff. Checks:OK: 7. Indexed: yes.

Exports:CalculateSCCellProportionsGenerateSCReferenceMarkerBasedDecompositionReferenceBasedDecompositionSeuratToExpressionSetSimulateData

Dependencies:BiobaseBiocGenericslimSolvelpSolveMASSquadprog