{
  "_id": "6af190851c36d7c6403e339a",
  "Type": "Package",
  "Package": "Unico",
  "Title": "Unified Cross-Omics Deconvolution",
  "Version": "0.1.0",
  "Authors@R": "c(\nperson(\"Zeyuan\", \"Chen\", , \"johnsonchen@cs.ucla.edu\", role = c(\"aut\", \"cre\")),\nperson(\"Elior\", \"Rahmani\", role = \"aut\")\n)",
  "Description": "UNIfied Cross-Omics deconvolution (Unico) deconvolves\nstandard 2-dimensional bulk matrices of samples by features\ninto a 3-dimensional tensors representing samples by features\nby cell types. Unico stands out as the first principled\nmodel-based deconvolution method that is theoretically\njustified for any heterogeneous genomic data. For more details\nsee Chen and Rahmani et al. (2024)\n<doi:10.1101/2024.01.27.577588>.",
  "License": "GPL-3",
  "URL": "https://cozygene.github.io/Unico/",
  "BugReports": "https://github.com/cozygene/Unico/issues",
  "VignetteBuilder": "knitr, rmarkdown",
  "Config/testthat/edition": "3",
  "Encoding": "UTF-8",
  "RoxygenNote": "7.2.3",
  "Config/pak/sysreqs": "cmake",
  "Repository": "https://cozygene.r-universe.dev",
  "Date/Publication": "2024-02-23 18:24:05 UTC",
  "RemoteUrl": "https://github.com/cozygene/unico",
  "RemoteRef": "HEAD",
  "RemoteSha": "5d44ded4f6ce93f545e103212305e4a7e8734ec1",
  "NeedsCompilation": "no",
  "Packaged": {
    "Date": "2026-11-09 08:59:44 UTC",
    "User": "root"
  },
  "Author": "Zeyuan Chen [aut, cre],\nElior Rahmani [aut]",
  "Maintainer": "Zeyuan Chen <johnsonchen@cs.ucla.edu>",
  "_user": "cozygene",
  "_type": "src",
  "_file": "Unico_0.1.0.tar.gz",
  "_fileid": "https://r2.ropensci.org/10dfff9f8b7922fdb0c5a81a21dbdfbdc90d6ac09a45aed712c7d6a506275a59",
  "_filesize": 2275644,
  "_sha256": "10dfff9f8b7922fdb0c5a81a21dbdfbdc90d6ac09a45aed712c7d6a506275a59",
  "_expires": "2027-02-17T09:18:05.000Z",
  "_created": "2026-11-09T08:59:44.000Z",
  "_published": "2026-11-09T09:21:09.004Z",
  "_upstream": "https://github.com/cozygene/unico",
  "_status": "success",
  "_maintainer": {
    "name": "Zeyuan Chen",
    "email": "johnsonchen@cs.ucla.edu",
    "login": "johnsonzychen",
    "description": "",
    "uuid": 22631360
  },
  "_jobs": [
    {
      "job": 129069128884,
      "time": 184,
      "config": "linux-devel-x86_64",
      "r": "4.7.0",
      "check": "OK",
      "artifact": "13661241333"
    },
    {
      "job": 129069128698,
      "time": 197,
      "config": "linux-release-x86_64",
      "r": "4.6.2",
      "check": "OK",
      "artifact": "13661067461"
    },
    {
      "job": 129069128784,
      "time": 118,
      "config": "macos-oldrel-arm64",
      "r": "4.5.3",
      "check": "OK",
      "artifact": "13660784719"
    },
    {
      "job": 129069129046,
      "time": 127,
      "config": "macos-release-arm64",
      "r": "4.6.2",
      "check": "OK",
      "artifact": "13662591094"
    },
    {
      "job": 129067287451,
      "time": 272,
      "config": "source",
      "r": "4.6.2",
      "check": "OK",
      "artifact": "13659864754"
    },
    {
      "job": 129069128776,
      "time": 115,
      "config": "wasm-release",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "13661440258"
    },
    {
      "job": 129069128752,
      "time": 122,
      "config": "windows-devel-x86_64",
      "r": "4.7.0",
      "check": "OK",
      "artifact": "13660419012"
    },
    {
      "job": 129069128706,
      "time": 82,
      "config": "windows-oldrel-x86_64",
      "r": "4.5.3",
      "check": "OK",
      "artifact": "13661166196"
    },
    {
      "job": 129069128759,
      "time": 111,
      "config": "windows-release-x86_64",
      "r": "4.6.2",
      "check": "OK",
      "artifact": "13660138939"
    }
  ],
  "_buildurl": "https://github.com/r-universe/cozygene/actions/runs/42589441754",
  "_commit": {
    "id": "5d44ded4f6ce93f545e103212305e4a7e8734ec1",
    "author": "Zeyuan Chen <johnsonchenzeyuan@gmail.com>",
    "committer": "Zeyuan Chen <johnsonchenzeyuan@gmail.com>",
    "message": "update gpl3 License link\n",
    "time": 1708712645
  },
  "_distro": "resolute",
  "_host": "GitHub-Actions",
  "_registered": true,
  "_dependencies": [
    {
      "package": "R",
      "version": ">= 4.0.0",
      "role": "Depends"
    },
    {
      "package": "compositions",
      "role": "Imports"
    },
    {
      "package": "config",
      "role": "Imports"
    },
    {
      "package": "data.table",
      "role": "Imports"
    },
    {
      "package": "futile.logger",
      "role": "Imports"
    },
    {
      "package": "MASS",
      "role": "Imports"
    },
    {
      "package": "matrixcalc",
      "role": "Imports"
    },
    {
      "package": "matrixStats",
      "role": "Imports"
    },
    {
      "package": "mgcv",
      "role": "Imports"
    },
    {
      "package": "nloptr",
      "role": "Imports"
    },
    {
      "package": "parallel",
      "role": "Imports"
    },
    {
      "package": "pbapply",
      "role": "Imports"
    },
    {
      "package": "pracma",
      "role": "Imports"
    },
    {
      "package": "stats",
      "role": "Imports"
    },
    {
      "package": "testit",
      "role": "Imports"
    },
    {
      "package": "utils",
      "role": "Imports"
    },
    {
      "package": "egg",
      "role": "Suggests"
    },
    {
      "package": "hexbin",
      "role": "Suggests"
    },
    {
      "package": "knitr",
      "role": "Suggests"
    },
    {
      "package": "rmarkdown",
      "role": "Suggests"
    },
    {
      "package": "testthat",
      "version": ">= 3.0.0",
      "role": "Suggests"
    }
  ],
  "_owner": "cozygene",
  "_selfowned": true,
  "_usedby": 0,
  "_updates": [],
  "_tags": [],
  "_stars": 7,
  "_userbio": {
    "uuid": 15380276,
    "type": "organization",
    "name": "cozygene",
    "followers": 14
  },
  "_downloads": {
    "count": 242,
    "source": "https://cranlogs.r-pkg.org/downloads/total/last-month/Unico"
  },
  "_devurl": "https://github.com/cozygene/unico",
  "_pkgdown": "https://cozygene.github.io/Unico/",
  "_searchresults": 6,
  "_rbuild": "4.6.2",
  "_assets": [
    "extra/citation.cff",
    "extra/citation.html",
    "extra/citation.json",
    "extra/citation.txt",
    "extra/contents.json",
    "extra/manual.pdf",
    "extra/NEWS.html",
    "extra/NEWS.txt",
    "extra/readme.html",
    "extra/readme.md",
    "extra/Unico.html"
  ],
  "_homeurl": "https://github.com/cozygene/unico",
  "_realowner": "cozygene",
  "_cranurl": true,
  "_releases": [
    {
      "version": "0.1.0",
      "date": "2024-02-26"
    }
  ],
  "_exports": [
    "association_asymptotic",
    "association_parametric",
    "simulate_data",
    "tensor",
    "Unico"
  ],
  "_help": [
    {
      "page": "association_asymptotic",
      "title": "Performs asymptotic statistical testing under no distribution assumption",
      "topics": [
        "association_asymptotic"
      ]
    },
    {
      "page": "association_parametric",
      "title": "Performs parametric statistical testing",
      "topics": [
        "association_parametric"
      ]
    },
    {
      "page": "simulate_data",
      "title": "Simulate data under Unico model assumption",
      "topics": [
        "simulate_data"
      ]
    },
    {
      "page": "tensor",
      "title": "Inferring the underlying source-specific 3D tensor",
      "topics": [
        "tensor"
      ]
    },
    {
      "page": "Unico",
      "title": "Fitting the Unico model",
      "topics": [
        "Unico"
      ]
    }
  ],
  "_readme": "https://github.com/cozygene/unico/raw/HEAD/README.md",
  "_rundeps": [
    "bayesm",
    "compositions",
    "config",
    "data.table",
    "DEoptimR",
    "formatR",
    "futile.logger",
    "futile.options",
    "lambda.r",
    "lattice",
    "MASS",
    "Matrix",
    "matrixcalc",
    "matrixStats",
    "mgcv",
    "nlme",
    "nloptr",
    "pbapply",
    "pracma",
    "Rcpp",
    "RcppArmadillo",
    "robustbase",
    "tensorA",
    "testit",
    "yaml"
  ],
  "_vignettes": [
    {
      "source": "Unico-Tutorial.Rmd",
      "filename": "Unico-Tutorial.html",
      "title": "Unico-Tutorial",
      "engine": "knitr::rmarkdown",
      "headings": [
        "Load the Unico package and",
        "Deconvolution on pseudobulk RNA expression data",
        "Cell-type level differential methylation analysis",
        "Perform association testing under no distribution assumption",
        "Calibration of asymptotically-derived p-values under null"
      ],
      "created": "2024-01-10 23:41:51",
      "modified": "2024-01-12 18:01:12",
      "commits": 5
    }
  ],
  "_score": 4.544068044350276,
  "_indexed": true,
  "_nocasepkg": "unico",
  "_universes": [
    "cozygene",
    "johnsonzychen"
  ],
  "_binaries": [
    {
      "r": "4.7.0",
      "os": "linux",
      "version": "0.1.0",
      "date": "2026-11-09T09:02:35.000Z",
      "distro": "resolute",
      "commit": "5d44ded4f6ce93f545e103212305e4a7e8734ec1",
      "fileid": "https://r2.ropensci.org/3f95a9644d8f4920ca9047e3f9d6155e8aaab45409f1f1ffe63a4606b8cf976d",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/cozygene/actions/runs/42589441754"
    },
    {
      "r": "4.6.2",
      "os": "linux",
      "version": "0.1.0",
      "date": "2026-11-09T09:02:46.000Z",
      "distro": "resolute",
      "commit": "5d44ded4f6ce93f545e103212305e4a7e8734ec1",
      "fileid": "https://r2.ropensci.org/5b14e398b6595f683390ec80dc20ae85a075b3189ed9bba42e6f05129f802fbd",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/cozygene/actions/runs/42589441754"
    },
    {
      "r": "4.5.3",
      "os": "mac",
      "version": "0.1.0",
      "date": "2026-11-09T09:16:50.000Z",
      "commit": "5d44ded4f6ce93f545e103212305e4a7e8734ec1",
      "fileid": "https://r2.ropensci.org/57fdfa89dc240d71c93aa59633e499ea44d73dc0fc96f68d132042bfcccb1e32",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/cozygene/actions/runs/42589441754"
    },
    {
      "r": "4.6.2",
      "os": "mac",
      "version": "0.1.0",
      "date": "2026-11-09T09:16:59.000Z",
      "commit": "5d44ded4f6ce93f545e103212305e4a7e8734ec1",
      "fileid": "https://r2.ropensci.org/bcc0d86060074eb26e5d2d00ff201a32036b767b26019ef29d0cbcf5da9bfbb9",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/cozygene/actions/runs/42589441754"
    },
    {
      "r": "4.6.0",
      "os": "wasm",
      "version": "0.1.0",
      "date": "2026-11-09T09:02:02.000Z",
      "commit": "5d44ded4f6ce93f545e103212305e4a7e8734ec1",
      "fileid": "https://r2.ropensci.org/8ba329ffa25987d850fd3cbaf7556fa3a7e8a6d5945e776173062aa78b17a0f7",
      "status": "success",
      "buildurl": "https://github.com/r-universe/cozygene/actions/runs/42589441754"
    },
    {
      "r": "4.7.0",
      "os": "win",
      "version": "0.1.0",
      "date": "2026-11-09T09:01:24.000Z",
      "commit": "5d44ded4f6ce93f545e103212305e4a7e8734ec1",
      "fileid": "https://r2.ropensci.org/8d7bf2d34e211d1457a0e4b226f7e4daf12db18ed69f35576cc1d13dd2cd1dd3",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/cozygene/actions/runs/42589441754"
    },
    {
      "r": "4.5.3",
      "os": "win",
      "version": "0.1.0",
      "date": "2026-11-09T09:00:57.000Z",
      "commit": "5d44ded4f6ce93f545e103212305e4a7e8734ec1",
      "fileid": "https://r2.ropensci.org/f159f7b247757476bd3070f19aeb9fa77991b4b06002c593607b215fa0c14475",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/cozygene/actions/runs/42589441754"
    },
    {
      "r": "4.6.2",
      "os": "win",
      "version": "0.1.0",
      "date": "2026-11-09T09:01:18.000Z",
      "commit": "5d44ded4f6ce93f545e103212305e4a7e8734ec1",
      "fileid": "https://r2.ropensci.org/ee23f386aebba9f78680ed6688a9f7f69883f32c58fdd4a868608218b90e69c0",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/cozygene/actions/runs/42589441754"
    }
  ]
}